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cAMP accumulation assay Peptide or small molecules stimulated cAMP accumulation was measured by a LANCE Ultra cAMP kit (PerkinElmer)

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This can lead to improved microcirculation, ensuring that oxygen and vital nutrients can once again reach oxygen-starved tissues in the brain and skeletal muscles

Thus, SP may function by interfering with the protein degradation process of KEAP1

Additional measurements included the systolic and diastolic blood pressures, serum lipids and fructosamine levels

Knapper J, Girauta MV, Coromina J