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The treatment is highly specific and exceptionally effective for musculoskeletal pathologies rooted in tissue failure or calcification, notably chronic tendonopathy

Cysteine is frequently identified as rate-limiting, or limiting the ability of glutathione synthesis based on lack of availability

As such, L-carnitine is believed to play a role in fat metabolism and energy production, and it has been used as a dietary supplement to enhance exercise performance and support weight loss

But the activity of GPX4 was all suppressed to varying degrees in cells treated with BSO, NS and NSBSO, respectively

doi:10.1016/j.repbio.2020.10.002

Lu, D.-Y