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There was no change in the trend of hypoglycemia events during follow-up
Gastrointestinal side effects like nausea may increase slightly when starting or escalating GLP-1 therapy alongside metformin
The starting dose is 0.25 mg per week, and the dose is slowly increased over 16 weeks until it reaches the maintenance dose
Geddes International Journal of Molecular Sciences.2021
Most GI symptoms improve over time once you're at a stable dose
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