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doi: 10.1016/j.cellsig.2024.111282 96 SunHSunZVargheseZGuoYMoorheadJFUnwinRJet al

Because the brain consumes a large amount of oxygen and leads to high production of reactive oxygen species, the antioxidative capacity of glutathione is important to keep brain homeostasis

Since DFO is membrane impermeable and accumulates in lysosomes 18 , we believe that it protects the cells against ferroptosis by chelating lysosomal iron as described previously 47

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SL-CAFs, senescence-like CAFs.

Safety Profile and Side Effects Black Box Warning: Vitamin B12 is highly safe and does not carry a formal FDA Black Box warning