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In addition, oral semaglutide must be taken with plain water on an empty stomach, and patients need to wait at least 30 minutes before eating or drinking anything else
The MHRA-approved Summaries of Product Characteristics (SmPCs) for semaglutide, liraglutide and tirzepatide do not list infertility as a recognised adverse effect, though clinical trials were not specifically designed to detect fertility issues
Obesity Pillars , 12 , 100127
For anyone on a GLP-1 whose fiber intake has quietly dropped, that built-in prebiotic fuel is doing double duty: nourishing the bacteria that support natural GLP-1, and helping keep things moving
Phase 3 trials are ongoing for both indications, positioning survodutide further along in clinical development
Consultation with a GP or prescribing clinician is essential before starting any laxative whilst on Wegovy to ensure appropriate individual management
