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Losing muscle can reduce metabolic rate, making it harder to sustain weight loss and leading to a host of other health issues, such as decreased strength and mobility
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The drug can reportedly cause side effects like nausea, diarrhea, vomiting, constipation, stomach discomfort and pain, injection site reactions, fatigue, allergic reactions (typically fever and rash), burping, hair loss and gastroesophageal reflux disease
Uchida, H
This is why the first question when someone asks "how much tirzepatide should I draw" is always "what's your vial concentration?" Compounding pharmacies choose concentration based on vial size, shelf-life considerations, and dose-range optimization
For weight loss purposes, doctors will start with a lower dosage of subcutaneous injections and slowly work up depending on how the patient reacts to the medication
