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NICE guideline NG222 for depression in adults does not include GLP-1 receptor agonists among recommended treatments
Patients who lose less than 5% of body weight by week 12 rarely achieve robust total weight loss by week 48
Using caution, however, is warranted, especially since there is no long-term data for humans
10.1016/j.molmed.2024.10.010 Trends Mol
The peptide can handle this without significant potency loss
They are not subject to the manufacturing standards that govern pharmaceutical production
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