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NF-B: at the borders of autoimmunity and inflammation
Liraglutide (Saxenda), semaglutide (Wegovy), and tirzepatide (Zepbound) are all FDA-approved for weight loss
Both patients described herein achieved rapid remission of long-standing, antihistamine-refractory CSU shortly after starting GLP-1RA therapy (semaglutide or tirzepatide), initially prescribed for metabolic indications
Side effects can generally be avoided by starting at a low dose and increasing the dose very slowly
Shake, mix in water or juice, and drink immediately
Do not assume that you simply need to push through a significant side effect
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