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The hallmark of epilepsy is the occurrence of epileptic seizures, which are characterized by predictable behavioral changes reflecting the underlying neural mechanisms of the disease
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Based on these characteristics, the incretin axis continues to be an attractive target for drug development, and GLP-1R agonists (GLP-1RA) have emerged as potent and effective treatments to reduce blood glucose and body weight 7
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Hydroxychloroquine also has glucose-lowering efficacy by increasing insulin sensitivity and improving pancreatic -cell function 178 , which has enabled hydroxychloroquine to be prescribed as an antidiabetic medication in some countries 179
It's worth noting that semaglutide has not been extensively studied in patients with severe gastrointestinal disease such as severe gastroparesis, and postmarketing reports have included cases of ileus
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