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Many people tolerate tirzepatide just fine with manageable side effects
So maybe just diet
Summary: GLP-1/GIP medications help reduce inflammation in metabolic organsnot autoimmune or pain-related inflammation They DO: lower CRP and related metabolic inflammatory/oxidative stress biomarkers, improve metabolic liver disease activity in steatohepatitis settings, improve cardiometabolic risk markers such as blood pressure improve kidney outcomes in high-risk CKD populations (semaglutide
Yonsei Med J 59(1):8591
Paradoxical Decreases in Heart Rate at Low Sub-Therapeutic Doses of Atropine (1) a central vagotonic mechanism , whereby low-dose atropine blocks inhibitory M1 muscarinic receptors in the central nervous system or parasympathetic ganglia, disinhibiting vagal outflow and increasing parasympathetic tone to the sinoatrial node (Kotona et al, 1977
This is why it is critical to stay hydrated, especially if you have pre-existing kidney issues or are experiencing significant GI side effects
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