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Discontinuation rates were slightly lower with tirzepatide, suggesting comparable tolerability
Lancet Diabetes Endocrinol 7(10):776785 Kosiborod MN, Abildstrm SZ, Borlaug BA, Butler J, Rasmussen S, Davies M, Hovingh GK, Kitzman DW, Lindegaard ML, Mller DV et al (2023) Semaglutide in patients with heart failure with preserved ejection fraction and obesity
The article explains that these medications work partly by resetting appetite centers in the brain, so when the drug is withdrawn suddenly, appetite hormones and metabolic signaling return to their baseline patterns and can trigger compensatory overeating
*PARA SUJETO A RESTRICCIONES: Para algunos medicamentos GLP-1 desde $149 con cupn del fabricante (sin seguro) en farmacias participantes de su preferencia
Cost Cost emerges as another significant barrier, with GLP-1RA and SGLT-2i being more expensive than insulin
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