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However, due to the disruption of organelle/cell integrity followed by a mixing of compartments and oxidation of GSH to GSSG, such estimates lack sub-cellular relevance [28], and dynamic measurements are impossible
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They also activate the Nrf2 pathway, enhancing antioxidant gene expression and cellular defenses against oxidative damage (Wang et al., 2021)
Pharmaceutical interventions targeting this system aim to restore or augment pulsatile GH secretion while preserving the physiological feedback mechanisms that prevent sustained supraphysiologic GH exposure
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Lopez-Santamarina A, Mondragon ADC, Cardelle-Cobas A, et al
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