Bevilacqua, Arturo, and Mariano Bizzarri
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2.6.3 Association mechanism between NADPH metabolic imbalance and ferroptosis Nicotinamide adenine dinucleotide phosphate (NADPH), is closely associated with the pathogenesis and progression of various metabolic diseases, and plays a pivotal role in ferroptosis regulation by modulating antioxidant system function and iron metabolism homeostasis, with its intracellular levels directly dictating cellular susceptibility to ferroptosis (145, 146)
One of B12s most important functions is its role in DNA synthesis and cell division
This selective senolytic action clears the aged, pro-inflammatory cells that drive tissue dysfunction with aging