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Tirzepatide does not directly cause B12 deficiency, but its appetite-suppressing effects may reduce intake of B12-rich foods like meat, fish, and dairy

It is essential to ensure that you are getting enough of it

Published studies used different routes, including oral and intravenous administration, so the amounts cannot be directly transferred between routes

The vial should be kept upright when possible and should not be shaken vigorously, as this could potentially cause foaming or degradation of the semaglutide peptide structure

Other causes Your body sometimes requires more folate than normal

Ganesan M, Solairaj P, Rajesh SC, Senthikumar T, Thangathirupathi A