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If tiredness persists or worsens over time rather than improving, this warrants discussion with your GP or diabetes specialist, as it may indicate the need for dose adjustment or additional investigation to exclude other causes of fatigue

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Gradual Dose Adjustment A slower increase in Retatrutide dosage may help the body adapt and could reduce the intensity of some treatment-related effects

Retatrutide has been associated with superior fat loss in trouble spots such as the belly and liver

The American College of Physicians guidelines note that continued treatment is necessary to maintain weight loss, as discontinuation often leads to weight regain