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Over time, the apparent heterogeneous nature of autism in clinical presentation, etiology, underlying neurobiology, and degree of severity led to the adoption and common usage of the term autism spectrum disorder (ASD) [347]
It is also worth noting that a close association between the feeding state and hepatic TH metabolism has been noticed early 16 , however, the regulatory role of hepatic TH signaling in response to feeding is largely unknown
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It occurs naturally in human plasma
