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Induced pluripotent stem cell-derived exosomes promote peripheral nerve regeneration in a rat sciatic nerve crush injury model: a safety and efficacy study

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It is being developed primarily as a treatment for obesity and type 2 diabetes, but its potential applications extend to several weight-related conditions including non-alcoholic fatty liver disease (NAFLD), knee osteoarthritis, and obstructive sleep apnoea

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With the exception of His1, the largest difference in the interaction of GLP-1 and exendin-4 occurred within the mid-region of the peptides where their sequences differ substantially (E 16 EAVRL 21 for exendin-4 vs G 22 QAAKE 27 for GLP-1)