Your GP or specialist will work with you to determine the most appropriate duration based on your treatment goals, response to therapy, and ability to maintain improvements through lifestyle measures alone
If you are looking for stronger weight loss, Mounjaro may be the better choice
In the pivotal trials, tirzepatide 15 mg achieved 22.5 per cent body weight in obesity alone (SURMOUNT-1) and clearly outperformed semaglutide head to head on diabetes weight loss (SURPASS-2)
However, Januvia requires dose adjustment in patients with renal impairment specifically, a reduction to 50 mg for eGFR 3044 and 25 mg for eGFR below 30
Where the mechanisms could synergize Three areas of potential synergy stand out in the theoretical analysis
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