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elevated triglycerides (defined as 150 mg/dL), decreased High Density Lipoprotein (HDL) (ranges below 40 mg/dL in men and 50 mg/dL in women), elevated blood pressure (defined as systolic blood pressure above 130 mmHg or diastolic blood pressure above 85 mmHg) and elevated fasting glucose (defined as blood glucose above 100 mg/dL)

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Timing Baseline Marker CRP Why it matters Can provide a general inflammation trend, although it does not show whether a local tendon or ligament is healing

Participants lost around 15% of body weight over 68 weeks, putting it roughly on par with standard injectable semaglutide