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JAK2 activation by growth hormone and other cytokines

Supplementary material The Supplementary Material for this article can be found online at: Glossary AD Alzheimers disease AI artificial intelligence ApoE apolipoprotein E Ascl1 Achaete-Scute bHLH factor 1 ASD Autism Spectrum Disorder BBB blood brain barrier BDNF brain-derived neurotrophic factor BrdU 5-bromo-2-deoxyuridine CAS core aging signature Cxcr4 CXC motif chemokine receptor 4 DCX Doublecortin DG dentate gyrus E embryonic day EED embryonic ectoderm development ETNPPL ethanol phosphate phospholipase FACS fluorescence-activated cell sorting GC granule cells GFAP glial fibrillary acidic protein GFP green fluorescent protein GO terms Gene Ontology terms Hopx Homeodomain-only protein IFN-gamma Interferon-gamma imGC immature GC IMPA1 inositol monophosphatase 1 IP intermediate progenitor IPs intermediate progenitors iPSC induced pluripotent stem cell KA kainic acid KDM4C histone lysine demethylase 4C L-RUN, H-RUN low or high runners lncRNAs long noncoding RNAs LPA1 lysophosphatidic acid receptor 1 LRRK2 leucine-rich repeat kinase 2 Mbd1 methyl-CpG-binding domain 1 MPTP 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine MTLE mesial temporal lobe epilepsy Nfix nuclear factor one X NPCs neural progenitor cells NSC neural stem cell O-GlcNAc O-linked -N-acetylglucosamine P postnatal day PRL Prolactin Prox1 Prospero homeobox 1 REST Repressor element 1-silencing transcription factor RGL radial glial like sc/snRNA-seq single-cell/single-nucleus RNA Sequencing SGZ subgranular zone SHR spontaneously hypertensive rats SI social isolation Sirt1 Sirtuin 1 Snca alpha-synuclein Sox2 Sex determining region Y-Box 2 SVZ subventricular zone TAPC transiently amplifying progenitor cell TBI traumatic brain injury VPA valproic acid

Instead of suppressing your appetite or forcing you to eat less, it targets the cellular machinery that tells your fat cells to store or release energy

(4) S Seiwerth, M Milavic, J Vukojevic, S Gojkovic, et al (2021)

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