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Bohnen NI, Kotagal V, Mller MLTM, Koeppe RA, Scott PJH, Albin RL, et al
In subjects with renal impairment including end-stage renal disease (ESRD), no change in tirzepatide pharmacokinetics (PK) was observed [see Clinical Pharmacology (12.3)]
The FTO gene variant (rs9939609) and MC4R gene variant (rs17782313) also shape your weight loss biology and may indicate whether you'll respond optimally to semaglutide alone or benefit from combination peptide therapy
This reduction in metabolic heat production could potentially manifest as feeling colder than usual, especially in cooler environments
Supports efficient metabolic function
