In the main trial (SURMOUNT-1) of 2,539 participants, adults with obesity or being overweight achieved up to 22.5% average weight loss over 72 weeks on the highest dose of tirzepatide, with lower doses also delivering substantial results
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BMC Res Notes 9:60 Diakogiannaki E, Gribble FM, Reimann F (2012) Nutrient detection by incretin hormone secreting cells
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