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Common side effects include: Most side effects are mild and temporary, often improving as your body gets used to the medication
report right upper quadrant pain to your GP or trial clinician Diabetic retinopathy worsening: Seek urgent ophthalmic review if you experience sudden changes in vision Hypoglycaemia: More relevant when retatrutide is used alongside insulin or sulphonylureas Injection site reactions: Persistent lumps, pain, or skin changes at injection sites should be assessed by a clinician When to seek help: Call 999 for severe chest pain, difficulty breathing, signs of severe dehydration (collapse, confusion), or suspected anaphylaxis Contact NHS 111 or your GP for persistent vomiting or diarrhoea, suspected pancreatitis, or any new or worsening symptoms that concern you There is currently no official MHRA safety profile for retatrutide, as it remains unlicensed
Orforglipron, an oral GLP-1RA, demonstrated significant Hb A 1c reduction and weight loss
If you struggle to eat enough in your main meals due to the hunger-lowering effects of Wegovy, then consider meals that are easier to digest, like soups with a side of protein (like boiled eggs, sliced chicken, or smoked salmon), smoothies, casseroles, bolognese, and scrambled eggs with vegetables
it is available only within authorised clinical trials via programmes such as the TRIUMPH Phase 3 study
This stands for benefits exclusion and means specific plans might not cover Saxenda
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