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Compared to wild-type BoNT/X protease, both X(PC2)b, an earlier evolutionary intermediate with activity on both VAMP1 and procaspase-1, and X(PC) demonstrated more stringent substrate requirements (Fig
F., & Onyeaka, H
10.1007/s40519-018-0481-6 5
It also helps regulate the immune response
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Curcumin is a diketone pigment composed of two ortho-methylated phenols and a -diketone functional group, with the -diketone portion believed to be responsible for its instability, rapid degradation, and low bioavailability (Vargas-Mendoza et al., 2022)
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