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Because the published Phase 2 pharmacology characterizes it as having comparable potency at all three receptors rather than being a single-receptor compound with weak off-target activity

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Consistent with the role of cholesterol in the regulation of membrane dynamics, cholesterol loading in mitochondrial membrane results in increased membrane order parameter and in the reduction in the activity of specific membrane carriers, i B via c-SRC and oxidant-dependent cell death

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It is essential for DNA repair, cellular survival, and energy metabolism