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Efficacy and safety of oral semaglutide with flexible dose adjustment versus sitagliptin in type 2 diabetes (PIONEER 7): a multicentre open-label randomised phase 3a trial
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However, fasting also predictably induces compensatory physiologic responses, such as increased appetite signaling and reduced energy expenditure, which may undermine long-term durability
Cederberg, K
Lipodystrophy Long-term use of insulin, including TOUJEO, can cause lipoatrophy (depression in the skin) or lipohypertrophy (enlargement or thickening of tissue) in some patients and may affect insulin absorption [see DOSAGE AND ADMINISTRATION ]
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