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5 Versatile therapeutic potentials of supersulfide donors in inflammatory diseases Endogenous and synthetic supersulfide donors, as summarized in Figure 9 , can penetrate cells and organs, delivering sulfur atoms to intracellular acceptors, thereby elevating supersulfide levels (103, 104)

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Key findings of the paper: Finding 1: NNMT is highly expressed in adipose tissue

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10.1016/j.bbrc.2019.02.142 Summary Keywords diabetic wound, inflammatory response, mitochondrial dysfunction, mtDNA leakage, NLRP3 inflammasome, oxidative stress Citation Chen Y, Li H and He W (2026) Mitochondria-mediated inflammation and diabetic wound healing: mechanisms and therapeutic strategies