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This is a theoretical concern from epidemiological data, not a demonstrated side effect of CJC-1295, but it warrants monitoring (Renehan et al., Lancet 2004)
10 ul of each drug solution was added to 90 ul of the rat blood serum samples and at specific time intervals the researchers terminated metabolism by adding 1 ml of ACN and acetic acid in order to precipitate the proteins which were then removed after overnight refrigeration followed by centrifugation
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doi: 10.1042/BSR20193160 292 LiGTanWFangYWuXZhouWZhangCet al
If wrinkles progressively worsen beyond six weeks or if the change is dramatic rather than subtle, stop and reassess
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