The induction of oxidative cell death emerges as a key strategy in the field of cancer therapeutics
Particular attention should be paid to possible side effects linked to the method of administration, like subcutaneous injections, which might cause local reactions such as redness, swelling, or irritation
The emerging hallmarks of cancer metabolism
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[3] The regulation of levels of ROS, levels of oxidized and reduced glutathione and other thiols, and antioxidant enzymes (such as GSTs and glutathione reductase) are important in determination of the most stable conditions for redox control, or for activation of apoptosis