Pentadecapeptide BPC 157, cimetidine, ranitidine, bromocriptine, and atropine effect in cysteamine lesions in totally gastrectromized rats: a model for cytoprotective studies
M.PimentelC.da SilvaS.CordeiroA
This study is to explore a GSH-responsive AP probe-net, which can be activated by the abundant GSH in ATC cells to generate reactive alkoxyamine, and the formed alkoxyamine can trap AP sites and block the APE1 activity, leading to ATC cell death but less adverse effects towards normal cells
This makes it a gentler alternative to harsher brightening ingredients that might cause irritation
Potential Side Effects: Generally well-tolerated, but possible side effects may include mild irritation at the injection site or allergic reactions
Biodegradable, hydrogen peroxide, and glutathione dual responsive nanoparticles for potential programmable paclitaxel release