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It is available in both injectable and oral formulations [2]
When someone comes to me with autoimmune disease, chronic inflammation, or toxic overload I dont have time to experiment
But the doses required (typically 5001,500 mg of berberine per day) are far beyond what a small patch can plausibly deliver through the skin, even before you account for the absorption barrier
Phentermine is approved for short-term use only, typically a few weeks
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