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To identify the cellular differences between the mouse and human liver responsible for the different injury response to alcohol we have generated humanized mice that can support human liver cells (parenchymal and non-parenchymal cells) along with human hematopoiesis [1]

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The brain is particularly vulnerable to oxidative damage due to its high oxygen consumption, abundant lipid content, and relatively low antioxidant capacity [151]

While they may offer potential benefits, it is important to be aware of the potential side effects and risks associated with this treatment

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FDA approval is expected in 2025-2026 if trials are successful