The Canadian context adds specific dimensions to weight-related anxiety
Maintaining hydration helps minimise side effects and supports optimal medication function
Contraindications Do not use DSIP if you: Are pregnant or breastfeeding (insufficient safety data) Have sleep apnea or other breathing-related sleep disorders (sedation risk) Take prescription sedatives or sleep medications Have a history of severe reactions to injected peptides Are under 18 years old If you have any chronic medical condition or take regular medications, consult a healthcare provider familiar with peptide therapies before starting DSIP

Contact a healthcare professional promptly or seek urgent care for: Severe or persistent abdominal pain, especially pain radiating to the back Right-upper-abdominal pain accompanied by fever, vomiting, or yellowing of the skin or eyes Persistent vomiting or diarrhea Inability to keep fluids down Very little urination Fainting, severe weakness, confusion, or signs of significant dehydration Symptoms of severe hypoglycemia Rapidly worsening symptoms after a dose increase These symptoms may require physical examination, imaging, medication review, or immediate treatment rather than direct-to-consumer testing alone
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Wright and Aroda, 2020) reported that both oral and injectable semaglutide were mostly discontinued due to gastrointestinal adverse effects