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doi: 10.3233/JPD-181474 80 PringsheimTJetteNFrolkisASteevesTDL
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Brain-derived GLP-1 pathways are generally not activated unless metabolic balance is disrupted, such as under stress conditions
Whilst these compounds have established biochemical functions, there is no robust randomised controlled trial evidence for clinically meaningful weight loss or fat reduction in replete individuals
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