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5-Oxoproline is converted to glutamate by the ATP-requiring enzyme 5-oxoprolinase

In particular, tell your provider if you have or had a past history of: Type 1 or type 2 diabetes Thyroid cancer Gastrointestinal disease Pancreatitis Kidney disease Diabetic retinopathy Tell your provider if you are pregnant, planning to become pregnant, or breastfeeding

Supplementing is often necessary to ensure optimal nutrition for both the mother and her babies