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Les effets sur la fonction crbrale Des tudes scientifiques ont dmontr que lactyl-L-carnitine possdait des proprits antioxydantes, pouvait protger du stress oxydatif et pouvait moduler les neurotransmetteurs crbraux comme lactylcholine, la srotonine et la dopamine
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14,38,39 Several therapies currently in clinical development target glucagon receptors in addition to incretin receptors due to the effects of glucagon on reducing food intake and increasing energy expenditure
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In mice, CHAC1/BOTCH promotes neuronal differentiation by inhibiting NOTCH1 and both its depletion and overproduction severely disrupt neurogenesis ( CHAC1/BOTCH in zebrafish leads to severe defects in brain, heart and myotome development, resulting in embryonic lethality, highlighting its conserved and essential role (Yadav et al., 2019)