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Overall GRADE would probably be low with high risk of publication bias
Who Should Use Extra Caution and When Provider Oversight Is Non-Negotiable Patients with Hashimoto's thyroiditis, Graves' disease, prior thyroid surgery, or TSH-suppressive therapy (e.g., thyroid cancer survivors) require closer monitoring during GLP-1 initiation
Age and Biological Sex Men tend to lose weight faster than women in the short term, largely because they generally carry more lean muscle and have a higher resting metabolic rate
Combined with mindful eating, exercise, adequate sleep, and avoiding sugary, ultra-processed foods, these strategies can help you maintain steady GLP-1 levels and support sustainable weight loss
