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Primary-source basis for the topical-versus-injectable route argument

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We do not encourage use of medications prescribed for human use in pets without first consulting with a primary care veterinarian

Age alone is a weaker reason than it is usually presented as: whole-blood NAD+ does not reliably fall with age, and the decline that does show up is tissue-specific and load-dependent

If it has been longer than 28 days or if the solution looks different from when you first mixed it, discard it and reconstitute a fresh vial