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p 75 years) T2D patients, glycemic management with a SU remains an option, but it should be dispensed with great caution given the elevated risk of adverse reactions such as hypoglycemia, its questionable cardiac safety, and renal impairment [49]

Berberine paired with semaglutide is another combination that some researchers explore for enhanced metabolic benefits

Patients log their food and track their weight, and weight loss medication may be incorporated as well

GLP-1 Receptor Agonists for Type 2 Diabetes and Their Role in Primary Care: An Australian Perspective

PDR was defined as an Early Treatment Diabetic Retinopathy Study (ETDRS) score 60 or above

One important caveat: IGF-1 LR3 retains its ability to bind the insulin receptor (IR), forming hybrid IGF1R/IR complexes