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For example, BPC-157 is based on a peptide found in human stomach juices, while TB-500 is related to a molecule found in many types of cells, called thymosin beta-4

The exact cause is not fully understood, but it may relate to the bodys response to the drug or dehydration

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Miller TR, Wagner JD, Baack BR, Eisbach KJ

These typically resolve with continued use and may relate to changes in sleep architecture as the body adjusts