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B12 supplementation is very safe and side effects are very rare, but supplementation is often required for life
It has shown benefit in mental health as well (depression, anxiety, bipolar disorder, etc.), again, in part by reducing neuro-inflammation.
Dietary intake of fish, n-3 polyunsaturated fatty acids, and risk of inflammatory bowel disease: a systematic review and meta-analysis of observational studies
10.1161/hypertensionaha.116.08192 72 ZhangY.ZhouG.ChenZ.GuanW.ZhangJ.BiM.et al (2020c)
R01 CA246807 (S.B.)
What are people sort of hung up on where you're like, ah, give it up
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