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This copper peptide gene regulation manifests in several clinically significant ways: Downregulation of Pro-Inflammatory Genes: It actively suppresses genes associated with inflammation, such as those in the IL-6 and NF-B pathways, which are major drivers of cellular aging

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The Go-Nt 31 construct containing the basic region within the -helix showed indeed a greater steady-state localization at the PM compared to Go-Nt 7

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