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This is exactly why the REDEFINE 4 trial exists
Lancet 2021 Phase 2 (monotherapy) Lau et al., n=706, 26 weeks
Physiol Rep (2019) 7:e13994
Anti-Wrinkle Effect: Reduces fine lines and improves skin texture
Ingredients: Glutathione Competitively inhibits melanin synthesis in the reaction of tyrosinase and L-DOPA by interrupting L-DOPA's ability to bind to tyrosinase during melanin synthesis
Oxygen consumption (VO 2 ), carbon dioxide production (VCO 2 ), RER, energy expenditure (kcal h 1 ) and locomotor activity (cm s 1 ) were recorded and collected in 15 min bins
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