Risks include slightly elevated chances of blood clots, stroke, and certain cancers with long-term use
Feng Y, Cai F, Chen L, Gu Y, Geng DC, Yang HL, et al
Scharfman HE, Goodman JH, Sollas AL
This benefit is likely due to GSEs antioxidant and anti-inflammatory effects
Safety profile: high Mechanism: incomplete Optimal SC dose: unvalidated If you choose to use it, do so consciously: Start at the minimum effective dose, track your outcomes, and adjust your protocol based on YOUR physiology
[13] Causality clue (mechanisms): NIH inpatient RCT (calories/macros/fibre matched): UPF diet led to ~+500 kcal/day intake and +0.9 kg in 2 weeks vs unprocessedimplicates palatability, eating rate, energy density, and structure , not just nutrients