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Upon challenge by oxidants Nrf2 does not undergo ubiquitination and is released from Keap1 as a result of the modification of cysteine residues in Keap1 and/or phosphorylation of Nrf2

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The gene expression changes the peptide triggers may be more important than continuous peptide presence

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In addition, plasma may have a low glutathione content and may be difficult to measure

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10.1080/03008207.2019.1665035 Summary Keywords knee osteoarthritis, oxidative stress, reactive oxygen species, cartilage, synovitis Citation Liu L, Luo P, Yang M, Wang J, Hou W and Xu P (2022) The role of oxidative stress in the development of knee osteoarthritis: A comprehensive research review

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Except for cows infused with HMTBa, milk protein concentration increased by 0.07% in cows treated both Mepron and Smartamine, while infusions of DL-Met contributed for an 0.08% increase in this parameter (Zanton et al., 2014)

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