Semaglutide or Tirzepatide, cannot be prescribed and should not be purchased by individuals with a BMI under 25, an eating disorder, diabetes, gallbladder disease, history of drug or alcohol abuse, recent bariatric surgery, pancreatitis, medullary thyroid cancer or a family history of it, diabetic retinopathy, multiple endocrine neoplasia type 2, or those who are pregnant, breastfeeding, or planning to become pregnant
Gradual weight reduction allows the skin's collagen and elastin fibres time to adapt and contract, whereas rapid lossparticularly in individuals over 40 or those who have lost significant amounts of weightoften outpaces the skin's natural remodelling capacity
Unlike anabolic steroids, it stimulates your own pituitary rather than replacing GH exogenously, which makes long-term use more feasible
[110] Hormonal effects represent a potential concern, particularly with long-term melatonin use
You no longer have to spend hours in a waiting room to access clinical expertise
Regular follow-up should include assessment of weight loss trajectory, tolerability, medication adherence, and renal function if significant GI symptoms occur