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Heres what the science says: Fat Metabolism and Endurance A 2011 study by Wall et al

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Reversible inhibition of mitochondrial complex I activity following chronic dopaminergic glutathione depletion in vitro: Implications for Parkinsons disease

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(1) Echothiophate irreversibly inhibits acetylcholinesterase, resulting in accumulation of acetylcholine within the synaptic cleft

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Finally If insulin sensitivity is priority #1 when evaluating either of these compounds, MOTS-c and SS-31 represent a mitochondrial-level approach to metabolic optimization that complements GH secretagogue protocols without the risk of blood glucose disruption

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