Gastrointestinal side effects are well-documented with GLP-1 therapy and may indirectly affect fluid balance
The 5,10-methenyl-THF is converted to 10-formyl-THF, which then feeds into the folate cycle, by the MTFDH1 encoded enzyme as described in N 10 -Formyltetrahydrofolate Synthesis section above
If you are worried that glutathione will make you sleepy during the day, timing is an important factor to consider
If small particulates are still observed after 15 minutes, incubate at room temperature for an additional 30 minutes, and leave the vial at 2C - 8C overnight
Li H, Dong S (2017) Recent advances in the preparation of Fmoc-SPPS-based peptide thioester and its surrogates for NCL-type reactions
Ruscoe JE, Rosario LA, Wang T, Gate L, Arifoglu P, Wolf CR, Henderson CJ, Ronai Z and Tew KD