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Novo Nordisk already has a pill form of semaglutide that is used for diabetes
We hypothesize that adding a long-acting GLP-1-RA can increase basal GLP-1 levels and, in combination with native post-prandial GLP-1 bolus restored after MBS, may be considered as a basal-bolus treatment for individuals with MBS failure (Fig
doi: 10.1056/NEJMc2001176 147
September 11, 2023
Timeline for Results Both medications follow similar timelines because they work through identical mechanisms
In the SURMOUNT-1 trial, participants at the highest dose lost an average of 22.5 percent of body weight over 72 weeks, one of the strongest results ever recorded in a pharmacological weight loss trial
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