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B12 injections skip the digestive system as they enter the bloodstream directly
PMID 9847106
J Ophthalmol 2012(1):831502 Lin A et al (2019) Bacterial keratitis preferred practice pattern
Chest 155:647
Caldini, R
However, in NDDs, chronic or overwhelming ER stress shifts the UPR toward maladaptive responses, contributing to neuronal dysfunction and death, e.g., Prolonged PERK activation has been implicated in AD, PD, and ALS, where it contributes to chronic ER stress and neuronal death
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